Hepatitis was found in patient. What is hepatitis caused by RNA-genome virus which is not able to reproduce itself without HBsAg?
+ hepatitis D
hepatitis А
hepatitis В
hepatitis С
hepatitis Е
What is taxonomic position of the hepatitis B virus? +Family Hepadnaviridae genus Orthohepadnavirus
Family Orthohepadnaviridae genus Hepadnavirus
Family Picornaviridae genus Hepatovirus
Family Paramyxoviridae genus Enterovirus
Family Paramyxoviridae genus Influenzavirus
2. What is form of the hepatitis B virus? +Spherical shape Bullet- shaped brick- shaped
Filamentous 3. Describe the genome structure of hepatitis B virus? +Double- stranded DNA
+Virus has long negative-sense DNA chain and short positive-sense DNA chain
Virus has short negative-sense DNA chain and long positive-sense DNA chain
Single- stranded, fragmented negative-sense RNA Single- stranded fragmented positive-sense RNA Double- stranded fragmented negative-sense RNA Single- stranded non fragmented negative-sense -RNA Single- stranded fragmented negative-sense -DNA 4. Give morphological characteristics to the hepatitis B virus nucleocapsid? +It has cubic symmetry type +It has envelop Has icosahedra type symmetry Has not envelop He has mixed symmetry type 5. Where is the hepatitis B virus reproduction in the cell? +In the nucleus In the cytoplasm It starts in the nucleus and ends in the cytoplasm It starts in the cytoplasm and ends in the nucleus 6. Indicate the antigenic structure of the hepatitis B causative agent? +HBs-antigen
+HBc- antigen
+HBe- antigen
hemagglutinin (HA) and neuraminidase (NA) nucleoprotein (NP) M- antigen F-antigen G-antigen 7. What are the entrance gates to the hepatitis B? +Genital mucous with sexual contact
+Placenta
+Blood
Upper respiratory tract Damaged skin Mucous membranes of the gastrointestinal tract 8. Is there virusemia with hepatitis B? +Yes No 9. Give the characteristic to the immunity, which formed at hepatitis B? +Local and general humoral cellular non sterile +There is autoimmunity No autoimmunity Local non-specific short cellular General group-specific humoral Local and general humoral non-protective Type-specific non-protective by delayed type 10. What complications may arise in the disease of hepatitis B? +Cirrhosis
+Tumor of liver
Bacterial superinfection Malfunction of the nervous and cardiovascular systems Renal failure Violation of liver function No complications 11. What materials are taken for laboratory investigation at the hepatitis B? +Genital secretion +Liquor +Blood Urine Faeces Arthropods
Autopsy material 12. Where is the accumulation of hepatitis B causative agent in virological investigation? +The virological method is not used
Cell culture of human embryo In the culture of human fibroblasts In the Vero culture In the body of laboratory animals 13. How is ndication of the hepatitis B causative agent in virological investigation? +None of the above is available Presence of clinical signs of infection or death of experimental animals CPE
HAT and hem-adsorbing Formation of the plaques on chicken embryos 14. How is identification of the hepatitis B causative agent in virological investigation? +None of the above is available
Using the CFT, HI IFT NT 15.What are serological tests for hepatitis B diagnosis? +PHAT +CFT +ELISA
IFT AT 16. What is the specific prophylaxis of hepatitis B? +Vaccinating by using the recombinant vaccines
+According the schedule of the immunization
+Groups at risk +γ - globulins +All population Serum
At the beginning of the epidemic season Alive, killed, chemicals, vaccines subunits
What is taxonomic position of the hepatitis C virus? +Family Flaviviridae, genus Hepacivirus
Family Picornaviridae, genus Hepatovirus
Family Hepadnaviridae, genus Orthohepadnavirus
Family Hepadnaviridae, genus Deltavirus
Family не встановлена, genus Hepacivirus
2. What is form of the hepatitis C virus? +Spherical shape Bullet- shaped Brick- shaped
Filamentous 3. Describe the genome structure of hepatitis C virus? +Single- stranded non fragmented positive-sense RNA
Double- stranded DNA
Virus has long negative-sense DNA chain and short positive-sense DNA chain
Virus has short negative-sense DNA chain and long positive-sense DNA chain
Single- stranded, fragmented negative-sense RNA Double- stranded fragmented negative-sense RNA Single- stranded non fragmented negative-sense -RNA Single- stranded fragmented negative-sense -DNA 4. Give morphological characteristics of the hepatitis C virus nucleocapsid? +It has cubic type symmetry
+It has not envelop It has icosahedra symmetry type It has mixed symmetry type 5. Where is hepatitis C virus reproduction in the cell? +In the cytoplasm In the nucleus It starts in the nucleus and ends in the cytoplasm It starts in the cytoplasm and ends in the nucleus 6. Indicate the antigenic structure of the hepatitis C causative agent? +HCV Ag
VP1-VP4
HBs-antigen
HBc- antigen
HBe- antigen
M- antigen F-antigen G-antigen 7. What are the entrance gates to the hepatitis C? +Blood
+Gegenital mucous with sexual contact
+Placenta
Mucous membranes of the gastrointestinal tract Upper respiratory tract Damaged skin 8. Is there virusemia with hepatitis C? +Yes No 9. Give the characteristic of the immunity, which formed at hepatitis C? +Local and general humoral long life +There is not autoimmunity There is autoimmunity Local non-specific short cellular General group-specific humoral Local and general humoral non-protective Type-specific non-protective by delayed type 10. What can complications appear after hepatitis C? +Cirrhosis
+Tumor of liver
No complications
Bacterial superinfection Malfunction of the nervous and cardiovascular systems Renal failure Violation of liver function 11. What materials are taken for laboratory investigation at the hepatitis C? +Blood Genital secretion Liquor
Faeces Urine Arthropods
Autopsy material 12. Where is the accumulation of hepatitis C causative agent in virological investigation? +The virological method is not used
Cell culture of human embryo In the culture of human fibroblasts In the culture Vero In the body of laboratory animals 13. How is indication of hepatitis C causative agent in virological investigation? +None of the above is available Presence of clinical signs of infection or death of experimental animals CPE
HAT and hem-adsorbing Formation of the plaques on chicken embryos 14. How is identification of hepatitis C causative agent in virological investigation? +None of the above is available
Using the CFT, HI IFT NT 15. What are serologicaltests used for diagnosis of hepatitis C? +ELISA
RIA
IFT AT
PHAT CFT 16. What is the specific prophylaxis of hepatitis C? +There is not specific prevention
Vaccinating by using the recombinant, killed vaccines
By epidemiological indications
γ - globulins Vaccinating by the immunization calendar All population Serum
At the beginning of the epidemic season Live, chemicals, subunits vaccines
17. How is making rapid diagnostic of the hepatitis C?
