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QUALITY OF LLFE IN CROHN'S DISEASE; RESULTS OF A CASE-CONTROL STUDY

S. SHIVANANDA, M. VAN BLANKENSTEIN, W.R. SCHOUTEN

Departments of Internal Medicine II and Surgery, University Hospital "Dijkzigt",

Rotterdam, THE NETHERLANDS

 

Hipothesis: Crohn's disease is a highly debilitating condition and surgery may ameliorate the problem.

Aims of the study: 1. To assess the quality of life of patients with Crohn's disease; 2. To assess patients satisfaction after drug or surgical treatment.

Materlals and methods: The study population in this survey consisted of 120 cases with established Crohn's and disease and 75 neibourhood controls of similar age, sex and social class and no prior history of chronic Gl disease. They were interviewed by trained personnel using measures of health related quality of the of live were of live out lined by Grogono and Woodgate.

The factors in the assessment ol quality of life were: Global well-being

Specific complaints in daily life

Impact of disease on family life

Impact of disease on employment

Patients satisfaction after drug or surgical treatment

Results:

Global assessment with Physical Health

1= Completely Satisfied. 2 = Principally Satisfied, 3 = Neither Satisfied nor Dissatisfied,4 = Relatively Dissatisfied, 5 = Very Dissatisfied.

 

Specific complaints in daily life. Three most important disease related complaints:

Abdominal pain n=76 (63%)

Chronic tiredness n=65 (54%)

Diarrhoea n=63 (52%)

 

 

73% had some complaints during remission.This rose to 97% during reactivation.

 

Impact of disease on family life

  Crohns disease (n=120) Controls (n=75) p
Married at some time 91% 96% n.s.
Mean number of children prior to diaqnosis 0.64 n.r.  
Mean number of children after diaqnosis 0.78 n.r.  
Mean number of children 1.4 1.9 ˂0.05
Divorced 8.3% 1.3% ˂0.03

 

Impact of disease on employment

  Crohns disease Controls Rate ratio p
Refused work because of illness 14% 3% 6.0 ˂0.01
Chose to change work because of illness 14% 3% 6.0 ˂0.01
Not allowed to work because of illness 39% 5% 11.4 ˂0.0001
Working part time because of illness 24% 1% 23.6 ˂0.0001

 

Patients satisfaction after drug or surgical treatment

Patient's evaluation of the benefits of surgery rapidly declined after the first resection and subsequently remainded uniformly low. However, their estimation of drug treatment improved and remained significantly better (X2=34. p<0.001).

 

 


Date: 2014-12-28; view: 895


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