THE INFLUENCE OF OZONE THERAPY ON THE POSTOPERATIVE COURSE IN PATIENTS WITH ACUTE BILIARY PANCREATITIS

B.A. AGAYEV, Z.E. JAFARLI

Scientific Surgical Center named after M.A. Topchubashev, Baku, AZERBAIJAN

At present, there is a clear tendency to the steady growth of the frequencies of hospitalization of patients with acute biliary pancreatitis (ABP) in surgical hospitals. In this connection the timely correction of emerging morphofunctional disorders of the pancreas may be one of the methods of increasing of the efficiency of treatment of patients with ABP.

The aim of the study: to study the effect of antioxidant therapy on the results of complex treatment of patients with acute pancreatitis.

Materials and methods: The study was based on a comparative analysis of complex treatment of 19 patients with acute cholecystopancreatitis treated in surgical gastroenterology department of the SSC named after acad. M.A. Topchubashev and clinical hospital No 5. All patients were performed urgent surgery based on the indication. Patients were divided into two groups: I group (control) (n = 9) consisted of patients of AP, in which treatment was based on the traditional method, II (the main) group (n = 10) consisted of patients in which traditional basic measures were supplemented by the use of ozone therapy in the combined treatment (through local and parenteral application). In both groups of patients no destructions in the pancreatic gland were observed.

Results: According to the results of comparative examinations conducted in the postoperative period, in patients of the second pain relief occurred faster that in the first group, dyspeptic signs disappeared more rapidly, bowel function restored, and the duration of temperature reaction lasted significantly shorter. Hyperthermia in patients of the second group was a fixed within 1,62 ± 0,26 days of hospital stay, that is in comparison with the first group of patients was significantly lower by 7.36%. On the 7th day of observation in the second group of patients as compared to the first, in the common blood test, the number of leukocytes, stab and segmented neutrophils significantly decreased, ESR decreased. There was observed decrease of the level of sugar, blood amylase, and urine diastase. Similar processes were observed in the first group of patients with AP, but in the second group they appeared earlier and more expressively. This is particularly important, as it prevents the progression of the inflammation in pancreas and prevents the formation of para-pancreatic complications. Faster rehabilitation of patients allowed significant shortening of the duration of stay in hospital by 1.9 beds per day.

Conclusions: The use of ozone therapy in combined treatment of patients with ABP makes it possible to achieve more rapid correction of homeostasis, to improve quality of clinical rehabilitation and reduce the length of stay of patients in the hospital. These circumstances show the feasibility of using ozone therapy in complex treatment of patients with acute biliary pancreatitis.

Date: 2014-12-28; view: 904