CLINICAL SIGNIFICANCE OF CHANGES OF VASCULAR HEMODYNAMICS OF THE ABDOMINAL CAVITY IN GASTRIC ULCER

S.G. BURKOV, L.V. BUKOVA

Polyclinic No 3 of the Office of the President of the RF, Moscow, RUSSIA

Peptic ulcer (UD) is one of the most common diseases of the digestive system. As ulcerogenesis, that is, chronicity and recurrence of ulcers are associated with insufficient of blood supply, disturbance of trophic affected tissues, the purpose of this study was to evaluate hemodynamic features of vessels of the abdominal cavity in patients with gastric UD, subject to the phase of the disease.

Materials and methods. Dopplerography of abdominal vessels: of the the celiac trunk / CT / spleen / SA / common hepatic / CPA / upper mesenteric and portal / PV / and spleen / SV / veins (linear velocity of blood flow in the veins, peak systolic, end-diastolic, volume velocity (VV) of blood flow in arteries, resistance index /RI/) was held in 45 patients with UD (25 men, 20 women) aged between 32-70 years (average age 54,2 ± 6,4 years) in the exacerbation phase, of the stage of red and white scar 6 months after the cicatrization of gastric ulcer.

Results. In the acute phase of UD there was observed significant increase of VB in CT up to 876.6 ml/min, SA up to 429.2 ml/min, the UMA to 551.2 ml / min, with a decrease of RI. Significant increase of VB in PV up to 711.99 ml/min and SV up to 329.8 MW ml / min was observed, which can be explained by the maximum blood flow to the lesion focus along the vessels supplying the stomach. At the same time there was observed a recrease of VB in CHA up to 357.3 ml/min, with an increase of RI. In phases of scarring decrease of VB in CT, SA and UMA, the increase of RI, increase of VB in CHA with the decrease of RI were observed. 6 months after the scarring of ulcers, there was observed further decrease of voluminous blood flow as compared to the phase of the white scar in CT, SA, UMA, BB and SV, with the increase in voluminous blood flow in CHA, which indicated the completion of the process of tissue regeneration. However, 8 patients had no changes in VB in CHA and BB in against the background of standard treatment (IPP + eradication therapy) in the process of scarring of the ulcer, in these patients, exacerbation of UD was observed in the next 6 months.

Conclusion. The results of this study can be used as a prognostic test to predict the development of acute gastric UD in the next 6 months after scarring of the ulcer.

Date: 2014-12-28; view: 965