CONECTIV TISUE DISEASES. LUPUS ERYTHEMATOSUS.

pr8.m content

function dy=pr8(x,y)

dy=zeros(2,1);

dy(1)=y(2);

dy(2)=((y(1)/x)-y(2))*(1/x)-y(1);

end

command line

[x,y]=ode45(@pr8,[1 10], [0.1 0.5]);

plot(x,y,'-k')

grid;

Syntax of ode45

[T,Y]=ode45(@DiffEquationFunction,[Tstart,Tfinal],StartVector).

Tstart i Tfinal - eto prakticheski diapazon X-coordinat

StartVector – eto nachal’noe znachenie Y

CONECTIV TISUE DISEASES. LUPUS ERYTHEMATOSUS.

Lupus erythematosus this is systemic diseases with complicated pathogeneses and expressive sun sensibility, meeting often by young women. Frequency are 48 ill people about 100 000.

General cause. There is virus’s conception in 1952 year Moolten and Clark succeed isolate out of blood ill virus clever call LE-cells phenomenon in vitro.

Last time corresponded by separation from ill lupus erythematosus viruses Cocsaci, Epstein-Bar long time including of organism und give modulated influence of immunology system.

There is immunological conception developing this conception discovery in 1948 year called LE phenomenon. It is immunoglobulin group Ig G and there is antibody for nucleoprotein. Then into Y-globular fraction blood separation complex autoantibody against blood elements: antierythrocytes, antitromdocytes,

antileucocytes and elements coagulation blood.

Characterized is presence antibody not only with nucleoprotein but as from DNK.

There is likeness of fragment DNK with cardiolipin that explanation false positive Wassermann reaction.

Lupus erythematosus look as bright example diseases of immune complex.

By all forms diseases decrease number T cell and increase B lymphocytes and discover increase number 0- cells that show about transgression differentiation lymphoid cells.

Genesis predisposition by ill lupus erythematosus look highly frequency antigen HLA – A11, B8,18,35, DR2, DR3.

More role of pathogeneses play condition neurohormonal regulation. Show more frequency developing diseases by women provocation role pregnancy, abortion, labor, hormonal contraception, transgression menstruation cycle, hyperestrogenic,

By ill men discover increase into serum estrogenic and decrease testosterone. Discover decrease is glucocorticoid, mineralocorticoid and androgen function adrenals. Often look is hypofunction thyroid gland.

Always suffer is nerves system; in the beginning diseases prevail process excitement then graduated development processes brakes on and rapidly exhaust nerves system.

Classification.

Chronically - 1.discoides 2. dissemination

Acute or systemically

Date: 2014-12-21; view: 935